Probing Structural Evolution and Crystallization in Supramolecular Gels: A Nonlinear Optical Study

Promovendus/a: Dong Chen

Promotor(en): Prof. dr. Stijn Van Cleuvenbergen, Prof. dr. ir. Wim Thielemans

Imagine a jelly that can change its texture and properties depending on how you treat it. This research explores special materials called supramolecular gels, specifically those made from a molecule called FmocFF. We discovered that these gels are far more dynamic and adaptable than previously thought, not just static structures. By using a special imaging technique, like a super-powered microscope (SHG microscopy), we could watch these gels transform in real-time, revealing how their environment (like different temperatures) dramatically influences their structure. This understanding allowed us to use these clever gels to precisely control how drug molecules crystallise, which is crucial for making medicines more effective. Ultimately, this work opens doors to designing smart materials for various uses, from better drug delivery to new ways of building novel materials.